DNMT1 knockdown mitigates sepsis-induced myocardial dysfunction by preventing TFAM-mediated mitochondrial DNA cytosolic escape and subsequent cGAS-STING to regulate macrophage M2 polarization

Biochemical Pharmacology 2026

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Authors: Min Li, Yang Liu, Kuo Qu, Yu Zhang, Hailing Yang
DOI: 10.1016/j.bcp.2026.117709
Cited by: 3
References: 60

Fields of Study & Subjects

interferon and immune responses Cardiac Fibrosis and Remodeling Immune cells in cancer

Publication details

Journal / source
Biochemical Pharmacology
Publisher
Elsevier BV
Volume
246
Pages
117709–117709
Publication date
14 January 2026
Language
EN