Half-life extension and immunogenicity in therapeutic proteins: mechanisms, trade-offs, and a decision framework

Biochemical Pharmacology 2026

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Authors: Yingping Chen, Yinchu Song, Yiwen Xie, Jianyi Pan
DOI: 10.1016/j.bcp.2026.117846
Cited by: 3
References: 170

Fields of Study & Subjects

vaccines and immunoinformatics approaches Protein purification and stability Monoclonal and Polyclonal Antibodies Research

Publication details

Journal / source
Biochemical Pharmacology
Publisher
Elsevier BV
Volume
248
Pages
117846–117846
Publication date
25 February 2026
Language
EN