Discovery of novel pyridazinone derivatives as EGFRWT/ EGFRT790M kinase inhibitors; design, synthesis, antitumor evaluation, and molecular dynamic simulations

Bioorganic Chemistry 2026

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Authors: Sara Y Ewieda, Eman M. Ahmed, Peter A. Halim, Shaymaa G. Ibrahim, Khaled M. Gouda, Mohnad Abdalla, Wafa Ali Eltayb, Mohamed T.M. Nemr

DOI: 10.1016/j.bioorg.2026.109486

Cited by: 17

References: 59

Fields of Study & Subjects

Synthesis and biological activity Colorectal Cancer Treatments and Studies Cancer therapeutics and mechanisms

References 59