Design, synthesis, and biological evaluation of hydrophobic-tagged poly (ADP-ribose) polymerase 1 (PARP1) degraders

Bioorganic Chemistry 2026

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Authors: Jiaqian Li, Yang Cui, Mengyu Xiong, Liying Zhang, Shuo Mu, Ziqi He, Hongcheng Zhu, Kaiyin Yang, Qidi Zhong
DOI: 10.1016/j.bioorg.2026.109507
Cited by: 0
References: 43

Fields of Study & Subjects

Protein Degradation and Inhibitors PARP inhibition in cancer therapy Synthesis and biological activity

Publication details

Journal / source
Bioorganic Chemistry
Volume
170
Pages
109507–109507
Publication date
18 January 2026
Language
EN