Design, synthesis and biological evaluation of novel isoalantolactone-benzylamine derivatives leading to the discovery of a PARP1 inhibitor with selective cytotoxicity against MCF-7 breast cancer cells

Bioorganic Chemistry 2026

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Authors: Bo Cui, Yulin Song, Xueran Wang, Yuxuan Wang, X Chen, Shuai Yu, Deao Man, Haidan Yuan, Guangchun Piao, Yushun Tian

DOI: 10.1016/j.bioorg.2026.109521

Cited by: 2

References: 32

Fields of Study & Subjects

PARP inhibition in cancer therapy Phytochemicals and Medicinal Plants Bioactive Compounds and Antitumor Agents

References 32