Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico

Bioorganic Chemistry 2026

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Authors: Yuxin Shen, Jun Wu, Lu Cao, Shiqi Jiang, Yan Chen, Ren-ai Xu, Ling Ji
DOI: 10.1016/j.bioorg.2026.109523
Cited by: 1
References: 34

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Cancer Hypoxia and Metabolism Hepatocellular Carcinoma Treatment and Prognosis

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
173
Pages
109523–109523
Publication date
19 January 2026
Language
EN