Integrating synthesis, pharmacological evaluation, and molecular dynamics simulation of novel 8-substituted theophylline hybrids as potential PDE-4B inhibitors, bronchodilators and antibacterial

Bioorganic Chemistry 2026

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Authors: Taha F.S. Ali, marina A. O. Yani, Ibrahim M. Salem, Hend Mamdoh, Mohamed F. Radwan, Tarek Salah Ibrahim, Eman A. M. Beshr, Alaa M. Hayallah
DOI: 10.1016/j.bioorg.2026.109591
Cited by: 1
References: 63

Fields of Study & Subjects

Phosphodiesterase function and regulation Phenothiazines and Benzothiazines Synthesis and Activities Asthma and respiratory diseases

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
172
Pages
109591–109591
Publication date
2 February 2026
Language
EN