Structure-guided discovery of 4-phenyl-5-p-tolyloxymethyl-4H-1,2,4-triazole thioethers as 15-lipoxygenase inhibitors using integrated in vitro, structure-activity relationship, in silico, cytotoxicity towards MCF-7 cell line, DNA docking and MD simulation methods

Bioorganic Chemistry 2026

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Authors: Deeba Nawaz, Bushra Bashir, Ambar Iqbal, Ayesha Momen, Muhammad Ashraf, Avinash Karkada Ashok, Ayesha Azhar, Naheed Riaz

DOI: 10.1016/j.bioorg.2026.109667

Cited by: 2

References: 98

Fields of Study & Subjects

Synthesis and biological activity Click Chemistry and Applications Synthesis and Biological Evaluation

References 98