Discovery of 4-[2.2]paracyclophanylthiazole derivatives as topoisomerase ll/malic enzyme 1 inhibitors modulating autophagy/apoptosis pathways in breast cancer therapy

Bioorganic Chemistry 2026

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Authors: Lamiaa E. Abd El-Haleem, Ashraf A. Aly, Asmaa Abd Elmoez Zaker Mohamed, Mariam T. Fahmi, Alan B. Brown, Olaf Fuhr, Tarek M. Okda, Marwa E. Abdelaziz, Eman J. El-Agroudy
DOI: 10.1016/j.bioorg.2026.109695
Cited by: 1
References: 65

Fields of Study & Subjects

Cancer therapeutics and mechanisms Synthesis and bioactivity of alkaloids Histone Deacetylase Inhibitors Research

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
174
Pages
109695–109695
Publication date
25 February 2026
Language
EN