Discovery of a pyrimidine-based steroidal FXR agonist for the treatment of metabolic dysfunction-associated steatotic liver disease

Bioorganic Chemistry 2026

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Authors: Xiaomin Zheng, Zhe Zhang, Xuwen Jiao, Mao Mu, Ang Yu Liu, Yao Huang, Weiping Wu, Chuanrong Liao, Yuhui Jiang, Weiyang Liang, Shan Li, Jing Li
+1 more Lei Zhang (38117)
DOI: 10.1016/j.bioorg.2026.109721
Cited by: 0
References: 54

Fields of Study & Subjects

Liver Disease Diagnosis and Treatment Drug Transport and Resistance Mechanisms Computational Drug Discovery Methods

Publication details

Journal / source
Bioorganic Chemistry
Volume
174
Pages
109721–109721
Publication date
4 March 2026
Language
EN