Towards the discovery of potent epigenetic modulators: Design, synthesis, biological evaluation, and SAR investigation of novel indole-based derivatives targeting HDAC1 and HDAC6

Bioorganic Chemistry 2026

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Authors: Sarah Shawky, Tarek Erfan Ahmed, Hesham Haffez, Aya Sobhy, Sameh H. Soror, Maiy Y. Jaballah, Nermin Samir, Maged Henary, Deena S. Lasheen
DOI: 10.1016/j.bioorg.2026.109772
Cited by: 3
References: 58

Fields of Study & Subjects

Histone Deacetylase Inhibitors Research Protein Degradation and Inhibitors Epigenetics and DNA Methylation

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
175
Pages
109772–109772
Publication date
19 March 2026
Language
EN