Discovery of 1,2-dihydro-4-hydroxy-2-oxoquinoline-3-carboxamide derivatives as potent anticancer agents: Structure-based design, synthesis, mechanistic insights, target identification, and molecular docking studies

Bioorganic Chemistry 2026

View at publisher
Authors: Neethu Mariam Thomas, Anoop Kallingal, Natalia Maciejewska, Munugala Chandrakanth, Deepak B. Salunke, Nikolai Petrovsky, Varun Thachan Kundil, J. Abhithaj, Majed Alharbi, Magdalena Narajczyk, Ramesh Gondru, Catherine Pasangha
+1 more Janardhan Banothu
DOI: 10.1016/j.bioorg.2026.109783
Cited by: 3
References: 40

Fields of Study & Subjects

Cancer therapeutics and mechanisms Synthesis and biological activity Quinazolinone synthesis and applications

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
175
Pages
109783–109783
Publication date
20 March 2026
Language
EN