Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studies

Bioorganic Chemistry 2026

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Authors: Hagar S. El-Hema, Rasha A.-S. El-Ghorab, Mohamed A. Hawata, Eman S. Nossier, Modather F. Hussein, Ahmed T. Elhendawy, Mohammed F. Hamza, Adel A. H. Abdel-Rahman
DOI: 10.1016/j.bioorg.2026.110052
Cited by: 1
References: 84

Fields of Study & Subjects

HER2/EGFR in Cancer Research Quinazolinone synthesis and applications Lung Cancer Treatments and Mutations

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
179
Pages
110052–110052
Publication date
27 May 2026
Language
EN