Design, synthesis, and evaluation of febuxostat derivatives bearing 1,2,3-triazole: potent inhibitors of microglia-mediated neuroinflammation and oxidative stress via Nrf2-HO-1 activation

Bioorganic Chemistry 2026

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Authors: Lan Wang, Xixi Hou, Xu Liang, Mingxuan Song, Dong Yan, Qingqing Zhang, Yimian Wang, En Gao, M Y Gao, Mengyuan Li, Jingjing Guo, Longfei Mao
+1 more Sanqiang Li
DOI: 10.1016/j.bioorg.2026.110128
Cited by: 1
References: 34

Fields of Study & Subjects

Tryptophan and brain disorders Genomics phytochemicals and oxidative stress Macrophage Migration Inhibitory Factor

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
180
Pages
110128–110128
Publication date
17 June 2026
Language
EN