Rational design and synthesis of dispiroindene-pyrrolidinedione scaffolds as multi-target directed ligands: potent AChE inhibitors with antioxidant activity and favorable biocompatibility in SH-SY5Y cells

Bioorganic Chemistry 2026

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Authors: Nagy A. Morsy, Riham A. El-Shiekh, Mohamad M. Ebrahium, Aladdin M. Srour
DOI: 10.1016/j.bioorg.2026.110245
Cited by: 1
References: 54

Fields of Study & Subjects

Cholinesterase and Neurodegenerative Diseases Enzyme function and inhibition Nicotinic Acetylcholine Receptors Study

Publication details

Journal / source
Bioorganic Chemistry
Publisher
Elsevier BV
Volume
180
Pages
110245–110245
Publication date
13 July 2026
Language
EN