Novel drug candidate binds to delta subunit containing GABAA receptors and improves spatial memory

Biomedicine & Pharmacotherapy 2026 Open access

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Authors: Orsolya Huzián, Lajos István Nagy, Laszlo Hackler, Levente Knapp, Agnes Katalin Kocsis, Ildikó Szöts, Gábor Tamás, László Géza Puskás, Gábor Molnár
DOI: 10.1016/j.biopha.2026.118970
Cited by: 0
References: 57

Abstract

receptors, which may contribute to the modulation of memory processes and serve as a protective mechanism in early-stage neurodegenerations. These receptor-mediated effects likely contribute to its broader therapeutic efficacy and may complement its previously reported interactions with signaling pathways such as NFAT and HIF-1.

Fields of Study & Subjects

Neuroscience and Neuropharmacology Research Pharmacological Receptor Mechanisms and Effects Nicotinic Acetylcholine Receptors Study

Publication details

Journal / source
Biomedicine & Pharmacotherapy
Volume
195
Pages
118970–118970
Publication date
6 January 2026
Language
EN