Targeting γ-aminobutyric acid type A receptors to mitigate perioperative neurocognitive disorders: a narrative review

British Journal of Anaesthesia 2026 Open access

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Authors: Joycelyn Ba, Connor T.A. Brenna, Lilia Kaustov, Dian-Shi Wang, Beverley A. Orser
DOI: 10.1016/j.bja.2026.01.004
Cited by: 5
References: 147

Abstract

receptors, and the implications of such mechanisms in perioperative neurocognitive disorders. On the basis of these insights, we propose several potential prevention and treatment strategies.

Fields of Study & Subjects

Intensive Care Unit Cognitive Disorders Anesthesia and Neurotoxicity Research Neuroscience and Neuropharmacology Research

Publication details

Journal / source
British Journal of Anaesthesia
Publisher
Elsevier BV
Volume
136
Issue
4
Pages
1235–1251
Publication date
4 February 2026
Language
EN