Novel 7-Substituted-1,2,4-Triazolopyrimidines targeting Nav1.2 channels as low-neurotoxicity antiepileptic agents

Bioorganic & Medicinal Chemistry 2026

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Authors: Yuxi Zhou, Weina Wang, Cui Lv, Jiahui Wu, Shuo Lv, Luqian He, Xinyu Zhao, Xi Qin, Binbin Tian, Renhao Chen, Chuanlong Guo, Longjiang Huang
+1 more Haibo Yu
DOI: 10.1016/j.bmc.2026.118550
Cited by: 1
References: 36

Fields of Study & Subjects

Chemical Reaction Mechanisms Pharmacological Effects and Toxicity Studies Quinazolinone synthesis and applications

Publication details

Journal / source
Bioorganic & Medicinal Chemistry
Publisher
Elsevier BV
Volume
134
Pages
118550–118550
Publication date
6 January 2026
Language
EN