An approach based on linear programming to build experimentally driven pump-leak models
Abstract
and by suppression of resting ion conductance. A simple computer application implementing this method is provided, offering a general strategy for parametrizing P-L models in different cell types.
Fields of Study & Subjects
Ion Transport and Channel Regulation
Ion channel regulation and function
Gene Regulatory Network Analysis
Publication details
- Journal / source
- Biophysical Journal
- Volume
- 125
- Issue
- 4
- Pages
- 1165–1184
- Publication date
- 14 January 2026
- Language
- EN