Effect of the gut microbiota metabolite phenylacetylglycine on cardiac Ca2+ signaling

Biophysical Reports 2026 Open access

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Authors: Elisa Bovo, Aleksey V. Zima
DOI: 10.1016/j.bpr.2026.100260
Cited by: 1
References: 19

Abstract

dynamics in ventricular myocytes by activating the adrenergic receptor-mediated signaling, but less efficiently than selective adrenergic agonists. By interacting with adrenergic receptors, PAGly might blunt the stimulatory effect of sympathetic stimulation.

Fields of Study & Subjects

Cardiac electrophysiology and arrhythmias Drug Transport and Resistance Mechanisms Gut microbiota and health

Publication details

Journal / source
Biophysical Reports
Publisher
Elsevier BV
Volume
6
Issue
2
Pages
100260–100260
Publication date
4 April 2026
Language
EN