At home monitoring of chronic adaptive deep brain stimulation for Parkinson's disease

Brain stimulation 2026 Open access

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Authors: Chuyi Cui, Jin Woo Choi, Shreesh Karjagi, Kevin B. Wilkins, Aarushi S. Negi, Helen M. Bronte-Stewart
DOI: 10.1016/j.brs.2026.103028
Cited by: 1
References: 9

Abstract

Exaggerated subthalamic nucleus (STN) beta oscillations and synchrony reflect pathological neural activity in Parkinson's disease (PD) and are associated with worsening of motor symptoms [1]. STN open-loop, continuous deep brain stimulation (cDBS) effectively alleviates motor symptoms but does not respond to dynamic fluctuations in pathological neural activity over time. Recent advancements in DBS systems have enabled local field potentials sensing and tracking of relevant neural biomarkers. Embedded control policy algorithms use these to adjust stimulation parameters in real time, known as adaptive deep brain stimulation (aDBS).

Fields of Study & Subjects

Neurological disorders and treatments EEG and Brain-Computer Interfaces Transcranial Magnetic Stimulation Studies

Publication details

Journal / source
Brain stimulation
Publisher
Elsevier BV
Volume
19
Issue
1
Pages
103028–103028
Publication date
1 January 2026
Language
EN