Auricular unified regulation of regions and afferents (AURORA): a multi-afferent auricular neuromodulation framework for depression

Brain stimulation 2026 Open access

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Authors: Jiani Wu, Sierra Hodges, Yu Liu, Kun Yan, Sean Yao, Yuanyuan Li, Jian Kong
DOI: 10.1016/j.brs.2026.103095
Cited by: 1
References: 7

Abstract

Auricular stimulation has attracted growing interest as a noninvasive neuromodulation strategy. The external ear is distinguished by convergent innervation from multiple cranial and cervical nerves, including the auricular branch of the vagus nerve (ABVN), the auriculotemporal branch of the trigeminal nerve (ATN), and cervical plexus contributions primarily via the great auricular nerve (GAN) and lesser occipital nerve (LON)[1].

Fields of Study & Subjects

Vagus Nerve Stimulation Research Neurological disorders and treatments Nerve injury and regeneration

Publication details

Journal / source
Brain stimulation
Publisher
Elsevier BV
Volume
19
Issue
3
Pages
103095–103095
Publication date
3 April 2026
Language
EN