Baseline tumor-informed circulating tumor DNA concentration predicts early chemoimmunotherapy failure in diffuse large B-cell lymphoma

Cancer Letters 2026 Open access

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Authors: Qing Shi, Muchen Zhang, Yang He, Ronggui Lin, Mingci CAI, Huijuan Zhong, Siyao Cheng, Pengpeng Xu, Weili Zhao, Li Wang
DOI: 10.1016/j.canlet.2026.218249
Cited by: 1
References: 27

Abstract

• Baseline circulating tumor DNA predicts early chemoimmunotherapy failure in DLBCL • Baseline circulating tumor DNA outperforms standard clinical risk scores for prognosis • Tumor-informed ctDNA testing offers a new tool for risk-adapted treatment strategy

Fields of Study & Subjects

Cancer Genomics and Diagnostics Lymphoma Diagnosis and Treatment CAR-T cell therapy research

Publication details

Journal / source
Cancer Letters
Publisher
Elsevier BV
Volume
640
Pages
218249–218249
Publication date
8 January 2026
Language
EN