ABCG2-mediated SN-38 efflux drives resistance to Sacituzumab govitecan in urothelial carcinoma

Cancer Letters 2026 Open access

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Authors: Isabella Prantl, Reinhard Grausenburger, Julia Müller, Oliver Baumfried, Iris E. Ertl, Christoph Nössing, Paula Herek, Christine Pirker, Daniel Valcanover, Yuri Bastos-Moreira, Eszter Borsos, Lena Marie Hauser
+12 more Luis Rupp, Ursula Lemberger, Lisa Gabler-Pamer, Ekaterina LAUKHTINA, Agata Suleja, André Oszwald, Gabriel Wasinger, Éva Compérat, Doris Marko, Shahrokh F. Shariat, Walter Berger, Bernhard Englinger
DOI: 10.1016/j.canlet.2026.218254
Cited by: 2
References: 38

Fields of Study & Subjects

Drug Transport and Resistance Mechanisms Wnt/β-catenin signaling in development and cancer Cholesterol and Lipid Metabolism

Publication details

Journal / source
Cancer Letters
Publisher
Elsevier BV
Volume
640
Pages
218254–218254
Publication date
13 January 2026
Language
EN