FIG4 downregulation-arrested autophagy-lysosomal degradation of IL-18 drives lipid-associated macrophage polarization and immunotherapy resistance in triple-negative breast cancer

Cancer Letters 2026

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Authors: Fada Xia, Xudong Zhu, X Li, Qiaoli Yi, Shangjun Zhou, Jiayu Wang, Xia Wang, Kejing Zhang, Cheng Zhan, Cheng Zhan, Hailin Tang, Zhijie Xu

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Huiting Zhang, Yuanliang Yan, Yuanliang Yan

DOI: 10.1016/j.canlet.2026.218278

Cited by: 9

References: 53

Fields of Study & Subjects

Autophagy in Disease and Therapy Inflammasome and immune disorders Immune cells in cancer

References 53