Sodium-glucose Cotransporter 2 Inhibition in Patients With Type 2 Diabetes and Chronic Kidney Disease Experiencing a Deterioration in Estimated Glomerular Filtration Rate to <20 mL/min/1.73 m2

Journal of Cardiac Failure 2026 Open access

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Authors: Safia Chatur, Robert A. Fletcher, Emily Yeung, Amanda Siriwardana, Lauren Heath, Muthiah Vaduganathan, Clare Arnott, Sunil Badve, Sradha Kotwal, Min Jun, Meg Jardine, Carol Pollock
+3 more Hiddo JL Heerspink, Vlado Perkovic, Brendon L Neuen
DOI: 10.1016/j.cardfail.2026.01.020
Cited by: 1
References: 21

Abstract

Background Clinical practice guidelines recommend initiation of SGLT2 inhibitors when eGFR ≥20ml/min/1.73m 2 . While continuing SGLT2 inhibitors when eGFR falls

Fields of Study & Subjects

Diabetes Treatment and Management Chronic Kidney Disease and Diabetes Pancreatic function and diabetes

Publication details

Journal / source
Journal of Cardiac Failure
Publisher
Elsevier BV
Volume
32
Issue
8
Pages
1408–1417
Publication date
27 February 2026
Language
EN