LAMPOON Followed by Valve-in-Valve-in-Ring for Transcatheter Mitral Valve Replacement

CASE 2026 Open access

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Authors: Ashleigh N Shenton, Nicholas Chan, Hanyuan Shi, Augustin J. DeLago, Michael N. Young, James T. DeVries, Lakshman Subrahmanyan
DOI: 10.1016/j.case.2025.11.009
Cited by: 1
References: 11

Abstract

Left ventricular outflow tract (LVOT) obstruction is a common and highly morbid complication of transcatheter mitral valve replacement (TMVR) procedures. LVOT obstruction after TMVR can have detrimental consequences, with in-hospital mortality as high as 62% if left untreated.1,2 Laceration of the anterior mitral leaflet to prevent outflow obstruction (LAMPOON) is a transcatheter method of mitigating LVOT obstruction after TMVR that can act as an alternative to surgical mitral valve (MV) replacement in patients at high risk for post-TMVR LVOT obstruction.

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Mechanical Circulatory Support Devices Atrial Fibrillation Management and Outcomes

Publication details

Journal / source
CASE
Publisher
Elsevier BV
Volume
10
Issue
3
Pages
93–98
Publication date
10 February 2026
Language
EN