Chemotherapy triggers immune evasion by fostering LEPR+ Kupffer cell differentiation in liver metastases

Cancer Cell 2026

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Authors: Xuege Wang, Qiang Pan, Yaqi Li, Ni Li, Jiacheng Guo, Yongqiang Gu, Guoying Zhang, Yannan Lian, Hailong Liu, Limin Cao, Wei Emma Zhang, Naiheng Lin
+12 more Beitao Xu, Zige Jin, Xin Zeng, Yi Zang, Xiaoyan Cheng, Hui Xiao, Sujun Chen, Moubin Lin, Guihua Wang, Junjie Peng, Yichuan Xiao, Jun Qin
DOI: 10.1016/j.ccell.2026.01.010
Cited by: 8
References: 83

Fields of Study & Subjects

interferon and immune responses Phagocytosis and Immune Regulation Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Cancer Cell
Publisher
Elsevier BV
Volume
44
Issue
3
Pages
658–675.e12
Publication date
12 February 2026
Language
EN