Tissue-fluid-driven symbiotic electronic textile accelerates and guides tissue self-healing

Electrical stimulation is a powerful strategy for promoting tissue self-healing, yet conventional systems are limited by reliance on external power sources, rigid components, and low conformability to dynamic tissue surfaces. Here, we report a tissue-fluid-driven, self-powered, fully bioresorbable symbiotic electronic textile (SBST) that integrates controllable electrical stimulation into a thin, breathable, and fully degradable textile while preserving essential wound-care functionality. By incorporating Magnesium (Mg)/Molybdenum (Mo) nanoelectrodes with an MXene ion-transport layer (80 ± 2.3 μm thick, 70 ± 3.1 mg), SBST avoids direct electrochemical contact with tissue and provides stable electrical output. In vivo studies demonstrate that SBST significantly enhances Achilles tendon regeneration in rats, accelerates skin wound healing, and exhibits effective antibacterial activity in mice and diabetic pigs. Its textile-compatible, lead-free design highlights SBST as a promising platform for next-generation, clinically translatable electrical stimulation therapies.