JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks

Cell Reports 2026 Open access

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Authors: Michael Van Meter, Matthew D. Simon, Gregory Tombline, Alfred May, Timothy D. Morello, Basil P. Hubbard, Katie Bredbenner, Rosa Park, David A. Sinclair, Vilhelm A. Bohr, Vera Gorbunova, Andrei Seluanov
DOI: 10.1016/j.celrep.2026.116960
Cited by: 1

Fields of Study & Subjects

Sirtuins and Resveratrol in Medicine PARP inhibition in cancer therapy DNA Repair Mechanisms

Publication details

Journal / source
Cell Reports
Publisher
Elsevier BV
Volume
45
Issue
1
Pages
116960–116960
Publication date
1 January 2026
Language
EN