The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK

Cell chemical biology 2026

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Authors: Jing Guo, Ping Wang, Wei Liu, Xin Shi, Wei Wu, Xi Zhang, Qiang Chen
DOI: 10.1016/j.chembiol.2026.04.003
Cited by: 1
References: 88

Fields of Study & Subjects

Metabolism Diabetes and Cancer PI3K/AKT/mTOR signaling in cancer Cancer-related Molecular Pathways

Publication details

Journal / source
Cell chemical biology
Publisher
Elsevier BV
Volume
33
Issue
6
Pages
767–784.e7
Publication date
1 May 2026
Language
EN