Incidence and Neoplastic Risk Associated with Colonic Stricture in Paediatric-Onset Crohn's Disease: A Population-based Study

Clinics and Research in Hepatology and Gastroenterology 2026 Open access

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Authors: Nicolas Richard, Ariane Leroyer, Claire Dupont, Dominique Turck, Valérie Bertrand, Pauline Wils, Corinne Gower‐Rousseau, Nathalie Guillon, Guillaume Savoye, Delphine Ley, Hélène Sarter, Mathurin Fumery
+88 more R Al Hameedi, M Al Khatib, S Al Turk, E Agoute, JM Andre, M Antonietti, A Aouakli, A Armand, L Armengol-Debeir, I Aroichane, F Assi, JP Aubet, E Auxenfants, A Avram, F Ayafi-Ramelot, K Azzouzi, D Bankovski, B Barbry, N Bardoux, P Baron, A Baudet, P Bayart, B Bazin, A Bebahani, JP Becqwort, S Bellati, V Benet, H Benali, C Benard, C Benguigui, E Ben Soussan, A Bental, I Berkelmans, J Bernet, K Bernou, C Bernou-Dron, P Bertot, N Bertiaux-Vandaële, V Bertrand, E Billoud, N Biron, B Bismuth, M Bleuet, F Blondel, V Blondin, M Bobula, P Bohon, V Bondjemah, E Boniface, D Bonkovski, P Bonnière, E Bonvarlet, P Bonvarlet, A Boruchowicz, R Bostvironnois, M Boualit, A Bouazza, B Bouche, C Boudaillez, C Bourgeaux, M Bourgeois, A Bourguet, A Bourienne, H Boutaleb, A.S. Bouthors, J Branche, G Bray, F Brazier, P Breban, M Bridenne, H Brihier, L Bril, V Brung-Lefebvre, P Bulois, P Burgiere, J Butel, JY Canva, V Canva-Delcambre, JP Capron, F Cardot, S Carette, P Carpentier, E Cartier, JF Cassar, M Cassagnou, JF Castex, P Catala, S Cattan
DOI: 10.1016/j.clinre.2026.102828
Cited by: 1
References: 17

Abstract

BACKGROUND: The identification of a colonic stricture in patients with Crohn's disease (CD) often leads to surgery due to concerns about colorectal cancer (CRC) risk. However, data on the risk associated with colonic strictures remain limited, particularly in paediatric-onset CD. OBJECTIVES: To evaluate the incidence of colonic stricture in CD and describe its natural course, focusing specifically on the risk of CRC. DESIGN: All patients diagnosed with CD

Fields of Study & Subjects

Inflammatory Bowel Disease Microscopic Colitis Colorectal Cancer Screening and Detection

Publication details

Journal / source
Clinics and Research in Hepatology and Gastroenterology
Publisher
Elsevier BV
Volume
50
Issue
6
Pages
102828–102828
Publication date
20 April 2026
Language
EN