The Prognostic Role of Interim [18F]FDG PET/CT in Diffuse Large B-Cell Lymphoma: An Updated Systematic Review and Meta-analysis

Clinical Lymphoma Myeloma & Leukemia 2026 Open access

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Authors: Domenico Albano, Stéphane Chauvie, Alessio Rizzo, Francesco Bertagna, Beatrice Casadei, Umberto Vitolo, Alessandra Tucci, Pier Luigi Zinzani, Luca Guerra
DOI: 10.1016/j.clml.2026.06.008
Cited by: 1
References: 82

Abstract

= 40.7%). In contrast, the prognostic effect of ΔSUV66% was weaker, with a pooled HR of 1.83. Scans performed after 4 cycles (iPET4, HR: 3.20) showed slightly stronger prognostic performance than those after 2 cycles (iPET2, HR: 2.84). Interim PET/CT, particularly when utilizing the DS 5 threshold, is a strong biomarker for identifying high-risk DLBCL patients.

Fields of Study & Subjects

Lymphoma Diagnosis and Treatment CNS Lymphoma Diagnosis and Treatment Medical Imaging Techniques and Applications

Publication details

Journal / source
Clinical Lymphoma Myeloma & Leukemia
Publisher
Elsevier BV
Volume
26
Issue
8
Pages
491–510.e1
Publication date
15 June 2026
Language
EN