Muscle atrophy associated with glucagon-like Peptide-1 receptor agonists: A population-based observational study

Clinical Nutrition 2026 Open access

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Authors: Angela T.H. Kwan, Moiz Lakhani, Roger S. McIntyre
DOI: 10.1016/j.clnu.2026.106620
Cited by: 3
References: 51

Abstract

> 0.. ConclusionsCertain GLP-1 receptor agonists demonstrate a pharmacovigilance signal of disproportionate reporting of muscle atrophy. These findings should be interpreted as signal detection rather than evidence of causality and highlight the need for future studies incorporating objective measures of muscle mass and function..

Fields of Study & Subjects

Diabetes Treatment and Management Adipose Tissue and Metabolism Muscle Physiology and Disorders

Publication details

Journal / source
Clinical Nutrition
Publisher
Elsevier BV
Volume
60
Pages
106620–106620
Publication date
4 March 2026
Language
EN