Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism

Cell Metabolism 2026

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Authors: Hongyu Qin, Jiamin Yu, Huan Yu, Chuqiao Zhou, Dongfeng Yuan, Ziling Wang, Zhenglin Zhu, Guizheng Wei, Peiyan Ou, Z. Li, Hua Jiang, Jie Shen
+7 more Guozhi Xiao, Xiaochun Bai, Huaiyu Wang, Huan‐Tian Zhang, John R. Speakman, Di Chen, Liping Tong
DOI: 10.1016/j.cmet.2026.01.008
Cited by: 19
References: 42

Fields of Study & Subjects

Diabetes Treatment and Management Osteoarthritis Treatment and Mechanisms Pain Mechanisms and Treatments

Publication details

Journal / source
Cell Metabolism
Publisher
Elsevier BV
Volume
38
Issue
3
Pages
582–597.e6
Publication date
9 February 2026
Language
EN