A review of point-of-care devices for blood-testing towards AI-driven remote digital care, precision healthcare and predictive medicine

ABSTRACT Point-of-care (POC) blood testing enables rapid, decentralized diagnostics with transformative promise, yet its innovation landscape remains poorly mapped. To this end, we focused on features that we believe are key to make progress in areas of precision healthcare and predictive medicine, such as longitudinal data collection and data analytics integration. While no review can be complete, this work attempts to address this gap by analyzing 86 POC blood testing devices worldwide and proposing a unified framework to compare them across technology principles, diagnostic breadth, usability, regulatory pathway, deployment feasibility (via a custom index), and data/AI integration. Electrochemical biosensors were the single largest platform (29.1%), strongly associated with glucose testing (χ 2 =237.8, p