1-oxa-3,7-diazaspiro[4.5]decan-2-one derivatives as potent KRAS-G12D inhibitors: A multidisciplinary approach integrating machine learning, synthesis, and biological evaluation

Computers in Biology and Medicine 2026

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Authors: Sungwook Ryu, Mohammad Hassan Baig, Umesh Panwar, Jae-June Dong, Yun Seong Jo, Chang Joong Kim, Sagar D. Nale, JiMin Park, Jain Ha, Byounggon Moon, Sangyoon Yi
DOI: 10.1016/j.compbiomed.2025.111437
Cited by: 1
References: 62

Fields of Study & Subjects

Protein Kinase Regulation and GTPase Signaling Receptor Mechanisms and Signaling Heat shock proteins research

Publication details

Journal / source
Computers in Biology and Medicine
Publisher
Elsevier BV
Volume
202
Pages
111437–111437
Publication date
2 January 2026
Language
EN