The correlation of stress hyperglycemia ratio with severe acute kidney injury among patients after cardiac surgeries: A retrospective study using the MIMIC database

Stress hyperglycemia ratio (SHR) has been identified as an independent risk factor for acute kidney injury (AKI) in specific populations. However, its relationship with severe AKI among patients undergoing cardiac surgeries remains unclear. This study aimed to explore the association between postoperative SHR and severe AKI in this population. A retrospective cohort study was conducted using data from the MIMIC-IV (v3.1) database. Adult patients (≥18 years) with first-time ICU admissions after cardiac surgeries were included. Severe AKI (KDIGO Stage II–III) served as the primary endpoint, while in-hospital death and ICU length of stay were secondary endpoints. Patients were divided into high SHR (≥1.256) and low SHR (