HT SpaceM enables high-throughput mapping of metabolic diversity at the single-cell level
Abstract
Expanding metabolomic profiling to the single-cell level can reveal metabolic heterogeneity and clinically relevant subpopulations, yet existing methods lack sensitivity and scale. To address this gap, in a recent issue of Cell, Delafiori and colleagues introduce HT SpaceM, a high-throughput MALDI workflow enabling sensitive, reproducible, and scalable single-cell metabolomics.
Fields of Study & Subjects
Metabolomics and Mass Spectrometry Studies
Mass Spectrometry Techniques and Applications
Single-cell and spatial transcriptomics
Publication details
- Journal / source
- Cell Reports Methods
- Volume
- 6
- Issue
- 1
- Pages
- 101268–101268
- Publication date
- 1 January 2026
- Language
- EN