Giant placental chorioangioma and intrapartum acute fetal distress: A case report

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Authors: Hung Nguyen Dao, Trung Viet Nguyen, Hieu Trung Mai, Tien Viet Tran, Tien Minh Bui, Kien Trung Nguyen, Tuan Dinh Le, Nui Minh Nguyen, Son Tien Nguyen, Hoa Trung Dinh, Binh Van Nguyen
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References: 6

Abstract

Placental chorioangioma represents the most frequent benign non-trophoblastic tumor of the placenta. Most lesions are small and clinically silent, but giant chorioangiomas (4–5 cm), while uncommon, can be associated with serious complications. This report describes the case of a 27-year-old woman (gravida 2, para 1) with an uneventful pregnancy until 33 weeks, when an ultrasound identified a placental mass measuring 60 × 70 mm. At 36 weeks, she presented with spontaneous rupture of membranes and labor pains. During labor, the fetus developed acute distress, and an emergency cesarean section was performed. A female infant weighing 2360 g was delivered with Apgar scores of 7 and 9 at 1 and 5 min. Intraoperatively, a well-circumscribed placental tumor measuring 10 × 10 cm was observed. Histopathological analysis confirmed chorioangioma. Both mother and newborn were discharged in good health on postoperative day 5. Although often silent during pregnancy, giant placental chorioangiomas may precipitate acute intrapartum complications. Vigilant antenatal monitoring and timely intervention are crucial to optimize perinatal outcomes. • Giant placental chorioangiomas are potentially serious lesions. • They may be clinically silent during pregnancy but go on to produce unexpected intrapartum complications. • Early detection, close antenatal surveillance, and prompt obstetric management are essential for improving perinatal outcomes for women with giant placental chorioangiomas.

Fields of Study & Subjects

Gestational Trophoblastic Disease Studies Pregnancy and preeclampsia studies Maternal and fetal healthcare

Publication details

Journal / source
Case Reports in Women s Health
Volume
50
Pages
e00799–e00799
Publication date
11 March 2026
Language
EN