Integrated metabolome and transcriptome analysis reveals ferroptosis involvement in cisplatin resistance of esophageal squamous cancer cell
Abstract
T cells and promoting ferroptosis. These findings indicate the critical role of ferroptosis and glutathione metabolism in the development and progression of ESCC. Meanwhile, APOBEC3B may serve as a promising therapeutic target for cisplatin-resistant ESCC cells.
Fields of Study & Subjects
Ferroptosis and cancer prognosis
Esophageal Cancer Research and Treatment
Cancer-related molecular mechanisms research
Publication details
- Journal / source
- Computational and Structural Biotechnology Journal
- Volume
- 31
- Pages
- 397–411
- Publication date
- 1 January 2026
- Language
- EN