Thermo-acoustic and spectroscopic approach for understanding molecular interactions between glycolic acid and B Vitamins

This study examines the thermodynamic properties of ternary mixtures containing D-Panthenol, niacin, and glycolic acid. At 0.1 MPa, experiments were conducted at temperatures ranging from 288.15 K to 318.15 K. The apparent and partial isentropic compression per mole was calculated using sound speed measurements. Key parameters, including the volume per mole apparent, the volume per mole partial, and the change in partial molar transfer volume, were determined using experimental density measurements. Solute-solvent interactions were found by pair and triplet coefficient analysis. The ternary mixture corresponding to the interactions of solvents and solutes is evaluated by computing the interaction coefficients using these thermodynamic parameters. Furthermore, determining values for specific heat ratio offers a more in-depth understanding of molecular behaviour and structural dynamics in these mixtures. An FTIR spectroscopic examination of the mixes (glycolic acid + water) and (glycolic acid + niacin/D-Panthenol) provided more insight into solute-solvent interactions. FTIR spectrum analysis confirmed the presence of H-bonds in the studied systems, as evidenced by the displacement of the O-H stretching band.