Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation

Developmental Cell 2026 Open access

Read full text
Authors: Xian Zhang, Wilfred Wong, Hyein S. Cho, Dapeng Yang, Gary Dixon, Renhe Luo, Dingyu Liu, Denis Torre, Shigeaki Umeda, Federico Gonzãlez, Gokce Askan, Aslihan Yavas
+18 more Jeyaram Ravichandran Damodaran, Robert W. Rickert, Rajya Kappagantula, Fong Cheng Pan, Victoria G. Aveson, Adrien Grimont, William B. Fall, Xianming Wang, Julián Pulecio, Samuel J. Kaplan, Heng Pan, Xianlu L. Peng, Jen Jen Yeh, Steven D. Leach, Christine A. Iacobuzio-Donahue, Rohit Chandwani, Christina S. Leslie, Danwei Huangfu
DOI: 10.1016/j.devcel.2026.04.012
Cited by: 1
References: 92

Fields of Study & Subjects

Pancreatic function and diabetes Pancreatic and Hepatic Oncology Research Pancreatitis Pathology and Treatment

Publication details

Journal / source
Developmental Cell
Publisher
Elsevier BV
Volume
61
Issue
6
Pages
1190–1207.e12
Publication date
19 May 2026
Language
EN