Draft genome dataset of Xylaria sp. KR-3U isolated from leaves of the medicinal plant Catharanthus roseus

leaves in India. Whole genome sequencing was performed using Illumina NovaSeq 6000 platform, generating 35.2 million paired-end raw reads (150 bp), providing ∼120× coverage (∼5.32 Gb of raw data) for a 44.24 Mb assembly (960 contigs >1 kb, GC content of 47.76%, and an N50 of 101,126 bp). Read remapping showed 96.07% alignment to the assembly. BUSCO (fungi_odb10) analysis indicated 97.0% completeness. Gene prediction using AUGUSTUS identified 11,916protein coding genes. BLASTp searches against the Swiss-Prot database yielded significant hits for 7299 proteins, of which 7204 were mapped to Gene Ontology (GO) terms and 5869 sequences received functional annotations . Integration of InterProScan-supported annotations resulted in 5645 proteins assigned at least one GO term. KEGG KAAS assigned 4,144genes (3,391KO numbers) to diverse pathways. Carbohydrate active enzyme (CAZyme) analysis revealed 556 CAZyme encoding genes, with 39.74% (221 genes) predicted to be secreted. antiSMASH detected 111 biosynthetic gene clusters (BGCs), including polyketide synthases (PKS), non-ribosomal peptide synthetases (NRPS), terpenes and hybrid clusters. The complete genome sequence and raw reads have been deposited in National Center for Biotechnology Information (NCBI) under the GenBank accession number JBSEFG000000000, BioProject number PRJNA1335662, BioSample ID SAMN52018968, and SRA (raw reads) accession number SRR35731853 The genome assembly (FASTA), gene annotation (GFF3), and secondary genome analysis files are deposited in Mendeley Data (Version 3; DOI: 10.17632/b8jn5rtwkg.3) under a CC BY 4.0 license to ensure transparency, reproducibility, and reuse of the analyses.