Clinical features and survival in primary intestinal lymphomas: A multicentre study

Digestive and Liver Disease 2026 Open access

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Authors: Nicola Aronico, Giovanni Santacroce, Marco Lucioni, Marco Vincenzo Lenti, Paola Ilaria Bianchi, Domenico Bagordo, Alessandro Vanoli, Giuseppe Neri, Carolina Ciacci, Fabiana Zingone, Umberto Volta, Luca Elli
+6 more Sara Massironi, Roberta Elisa Rossi, Gino Roberto Corazza, Luca Arcaini, Marco Paulli, Antonio Di Sabatino
DOI: 10.1016/j.dld.2025.12.029
Cited by: 1
References: 28

Abstract

BACKGROUND: Primary intestinal B-cell (IBCL) and T-cell (ITCL) lymphomas are rare and poorly characterized entities. AIM: To compare clinical features and survival outcomes of IBCL and ITCL. METHODS: We conducted a multicentre, retrospective study including patients diagnosed with primary intestinal lymphoma between 2001 and 2024. Clinical and laboratory variables were analysed using univariate and multivariate logistic regression. Discriminatory accuracy was assessed through ROC analysis. Overall survival was estimated with Kaplan-Meier curves. RESULTS: Ninety-four patients (41 IBCL and 53 ITCL) were included. IBCL were more frequently diagnosed at Lugano stage I (90% vs 5.7%; p

Fields of Study & Subjects

Lymphoma Diagnosis and Treatment Gastrointestinal Tumor Research and Treatment Esophageal Cancer Research and Treatment

Publication details

Journal / source
Digestive and Liver Disease
Publisher
Elsevier BV
Volume
58
Issue
4
Pages
541–548
Publication date
13 January 2026
Language
EN