Left Ventricular Myocardial Work Index: The Impact of Including Ventricular Diastolic Pressure

Journal of the American Society of Echocardiography 2026 Open access

Read full text
Authors: João Filipe Fernandes, Otto Armin Smiseth, Pablo Lamata, Brett Sydney Bernstein, Theodoros Kalos, Amanda Q. X. Nio, Kazuaki Wakami, Kevin G O'Gallagher, Alexandros Papachristidis, Nobuyuki Ohte
DOI: 10.1016/j.echo.2026.01.005
Cited by: 0
References: 7

Abstract

Clinical assessment of left ventricular (LV) systolic function by echocardiography is based on ejection fraction or myocardial strain, which are afterload dependent. An alternative measure of systolic function that incorporates afterload is myocardial work calculated as the area of the LV pressure-volume loop, an approach requiring invasive data.1 The most accepted noninvasive alternative is the global myocardial work index (GWI), which is calculated from LV pressure-strain analysis and includes a noninvasive estimate of the systolic segment of the LV pressure curve.

Fields of Study & Subjects

Cardiovascular Function and Risk Factors Cardiac Imaging and Diagnostics Cardiac Valve Diseases and Treatments

Publication details

Journal / source
Journal of the American Society of Echocardiography
Volume
39
Issue
5
Pages
520–522
Publication date
4 February 2026
Language
EN