Environmental occurrence, human exposure and multidimensional toxicity effects of 2-ethylhexyl diphenyl phosphate (EHDPP): Toxicological mechanism analysis and future research prospects

Ecotoxicology and Environmental Safety 2026 Open access

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Authors: Yaole Wu, Shuqi Liu, Hao Dong, Jinming Zhang, Rui Lü, Qiyu Yang, Rummana Jaman, Junmin Zhu, Conglin Zhang, Jiaqi Zhou
DOI: 10.1016/j.ecoenv.2026.119810
Cited by: 3
References: 122

Abstract

2-Ethylhexyl diphenyl phosphate (EHDPP) is one of the most abundantly used organophosphate esters (OPEs). Owing to its excellent flame-retardant and plasticizing properties, EHDPP has been applied in various diverse fields, such as packaging materials, building, and electronic products. Environmental monitoring data have revealed that EHDPP was presented in multiple environmental media, including soil, water, and air. EHDPP is able to penetrate the human body via skin contact, dietary exposure, and respiratory inhalation. Studies have detected EHDPP in human serum (

Fields of Study & Subjects

Toxic Organic Pollutants Impact Effects and risks of endocrine disrupting chemicals Pesticide Exposure and Toxicity

Publication details

Journal / source
Ecotoxicology and Environmental Safety
Publisher
Elsevier BV
Volume
310
Pages
119810–119810
Publication date
1 January 2026
Language
EN