Rational design of an NLRP3 inhibitor with superior efficacy and safety for gout therapy

European Journal of Medicinal Chemistry 2026

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Authors: Yichao Kong, Mengjun Su, Caihong Jiang, Haonan Feng, Yingjie Hu, Donglai Li, Zhenyu Mao, Fengling Liu, Fuli Zhu, Yue Guo, Shuhua Ren, Man Chi
+5 more Ting Qiu, Yaxia Yuan, Weiwei Huang, Lei Ma, Xiabin Chen
DOI: 10.1016/j.ejmech.2026.118578
Cited by: 1
References: 51

Fields of Study & Subjects

Gout Hyperuricemia Uric Acid Inflammasome and immune disorders Hepatitis C virus research

Publication details

Journal / source
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Volume
305
Pages
118578–118578
Publication date
13 January 2026
Language
EN