Structure-activity relationship of N-cyclopropylmethyl-7α-(m-methylaminophenyl)-6,14-endoethano-northebaine derivatives as G-protein-biased KOR-selective agonists

European Journal of Medicinal Chemistry 2026

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Authors: Siyuan Tang, Jiangwen Gui, Yingjie Lan, Panwen Liu, Yuliang Lin, Meng Sun, Shaoliang Duan, Chao Zhang, Denggao Zhang, Min Liu, Xiaobo Mai, Jiaqi Tan
+6 more Zhiwen Wang, Jinggen Liu, Liming Shao, Wei Fu, Yujun Wang, Wei Li
DOI: 10.1016/j.ejmech.2026.118591
Cited by: 1
References: 41

Fields of Study & Subjects

Neuropeptides and Animal Physiology Peptidase Inhibition and Analysis Receptor Mechanisms and Signaling

Publication details

Journal / source
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Volume
306
Pages
118591–118591
Publication date
17 January 2026
Language
EN