Semi-rigid linkers improve the pharmacokinetic properties and therapeutic efficacy of BET PROTACs for cancer therapy

European Journal of Medicinal Chemistry 2026

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Authors: Su Yu, Shichuan Hu, Weilin Wang, Chuntao Pan, Hongjia Zhang, Cong Zhou, Yang Liu, Rui Li
DOI: 10.1016/j.ejmech.2026.118644
Cited by: 2
References: 46

Fields of Study & Subjects

Protein Degradation and Inhibitors Chromatin Remodeling and Cancer Click Chemistry and Applications

Publication details

Journal / source
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Volume
307
Pages
118644–118644
Publication date
3 February 2026
Language
EN